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Suppression of P2X7R by Local Treatment Alleviates Acute Gouty Inflammation

OBJECTIVE: Gout is the most common inflammatory arthritis associated with interleukin-1β (IL-1β) accumulation during exacerbation. In this study, we aimed to clarify whether potassium channel antagonists attenuate local inflammation in mice with monosodium urate (MSU)-induced gout. METHODS: We cultu...

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Detalles Bibliográficos
Autores principales:	Zhao, Yang, Li, Zhiyuan, Chen, Ying, Li, Yushuang, Lu, Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460186/ https://www.ncbi.nlm.nih.gov/pubmed/37636273 http://dx.doi.org/10.2147/JIR.S421548

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