Predictors of alcohol and substance use among people with post-traumatic stress disorder (PTSD): findings from the NESARC-III study

PURPOSE: The self-medication hypothesis suggests people may develop Alcohol Use Disorder (AUD) or Non-Alcohol Substance Use Disorder (NA-SUD) following PTSD as a maladaptive way of coping with PTSD symptoms. Given that an accumulation of trauma experiences and interpersonal trauma increase the likel...

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Autores principales: Dell’Aquila, Adriana, Berle, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460312/
https://www.ncbi.nlm.nih.gov/pubmed/37133523
http://dx.doi.org/10.1007/s00127-023-02472-6
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author Dell’Aquila, Adriana
Berle, David
author_facet Dell’Aquila, Adriana
Berle, David
author_sort Dell’Aquila, Adriana
collection PubMed
description PURPOSE: The self-medication hypothesis suggests people may develop Alcohol Use Disorder (AUD) or Non-Alcohol Substance Use Disorder (NA-SUD) following PTSD as a maladaptive way of coping with PTSD symptoms. Given that an accumulation of trauma experiences and interpersonal trauma increase the likelihood and severity of PTSD, we sought to determine whether the number and type of traumas additionally predict AUD and NA-SUD following PTSD. METHODS: We analysed data from 36,309 adult participants in the National Epidemiologic Survey on Alcohol and Related Conditions-III (NESARC-III) study (M = 45.63 years, SD = 17.53, 56.3% female) who were administered semi-structured diagnostic interviews of trauma exposure and PTSD, AUD and NA-SUD symptoms. RESULTS: Individuals with PTSD were more likely to have an AUD or NA-SUD than those without PTSD. Endorsement of a greater number of traumas was associated with greater odds of having PTSD, AUD, or NA-SUD. Experience of interpersonal trauma was related to greater odds of having PTSD and subsequent AUD or NA-SUD than not experiencing interpersonal trauma. Multiple experiences of interpersonal trauma compared to one interpersonal trauma exposure also increased the odds of having PTSD followed by AUD or NA-SUD. CONCLUSIONS: Interpersonal trauma and multiple experiences of interpersonal trauma may result in individuals turning to alcohol and substances as a way to alleviate intolerable PTSD symptomology, aligning with the self-medication hypothesis. Our findings highlight the importance of ensuring services and support for interpersonal trauma survivors and for those who have experienced multiple traumas given their increased for unfavourable outcomes. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00127-023-02472-6.
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spelling pubmed-104603122023-08-28 Predictors of alcohol and substance use among people with post-traumatic stress disorder (PTSD): findings from the NESARC-III study Dell’Aquila, Adriana Berle, David Soc Psychiatry Psychiatr Epidemiol Research PURPOSE: The self-medication hypothesis suggests people may develop Alcohol Use Disorder (AUD) or Non-Alcohol Substance Use Disorder (NA-SUD) following PTSD as a maladaptive way of coping with PTSD symptoms. Given that an accumulation of trauma experiences and interpersonal trauma increase the likelihood and severity of PTSD, we sought to determine whether the number and type of traumas additionally predict AUD and NA-SUD following PTSD. METHODS: We analysed data from 36,309 adult participants in the National Epidemiologic Survey on Alcohol and Related Conditions-III (NESARC-III) study (M = 45.63 years, SD = 17.53, 56.3% female) who were administered semi-structured diagnostic interviews of trauma exposure and PTSD, AUD and NA-SUD symptoms. RESULTS: Individuals with PTSD were more likely to have an AUD or NA-SUD than those without PTSD. Endorsement of a greater number of traumas was associated with greater odds of having PTSD, AUD, or NA-SUD. Experience of interpersonal trauma was related to greater odds of having PTSD and subsequent AUD or NA-SUD than not experiencing interpersonal trauma. Multiple experiences of interpersonal trauma compared to one interpersonal trauma exposure also increased the odds of having PTSD followed by AUD or NA-SUD. CONCLUSIONS: Interpersonal trauma and multiple experiences of interpersonal trauma may result in individuals turning to alcohol and substances as a way to alleviate intolerable PTSD symptomology, aligning with the self-medication hypothesis. Our findings highlight the importance of ensuring services and support for interpersonal trauma survivors and for those who have experienced multiple traumas given their increased for unfavourable outcomes. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00127-023-02472-6. Springer Berlin Heidelberg 2023-05-03 2023 /pmc/articles/PMC10460312/ /pubmed/37133523 http://dx.doi.org/10.1007/s00127-023-02472-6 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Research
Dell’Aquila, Adriana
Berle, David
Predictors of alcohol and substance use among people with post-traumatic stress disorder (PTSD): findings from the NESARC-III study
title Predictors of alcohol and substance use among people with post-traumatic stress disorder (PTSD): findings from the NESARC-III study
title_full Predictors of alcohol and substance use among people with post-traumatic stress disorder (PTSD): findings from the NESARC-III study
title_fullStr Predictors of alcohol and substance use among people with post-traumatic stress disorder (PTSD): findings from the NESARC-III study
title_full_unstemmed Predictors of alcohol and substance use among people with post-traumatic stress disorder (PTSD): findings from the NESARC-III study
title_short Predictors of alcohol and substance use among people with post-traumatic stress disorder (PTSD): findings from the NESARC-III study
title_sort predictors of alcohol and substance use among people with post-traumatic stress disorder (ptsd): findings from the nesarc-iii study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460312/
https://www.ncbi.nlm.nih.gov/pubmed/37133523
http://dx.doi.org/10.1007/s00127-023-02472-6
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