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Assembly landscape for the bacterial large ribosomal subunit

Assembly of ribosomes in bacteria is highly efficient, taking ~2-3 min, but this makes the abundance of assembly intermediates very low, which is a challenge for mechanistic understanding. Genetic perturbations of the assembly process create bottlenecks where intermediates accumulate, facilitating s...

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Detalles Bibliográficos
Autores principales: Sheng, Kai, Li, Ning, Rabuck-Gibbons, Jessica N., Dong, Xiyu, Lyumkis, Dmitry, Williamson, James R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460392/
https://www.ncbi.nlm.nih.gov/pubmed/37633970
http://dx.doi.org/10.1038/s41467-023-40859-w