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SPDEF enhances cancer stem cell-like properties and tumorigenesis through directly promoting GALNT7 transcription in luminal breast cancer

BACKGROUND: Luminal breast cancer (BC) is the predominant subtype of breast cancer with a sustained risk of late recurrence and death. Understanding the molecular mechanisms for the oncogenesis of luminal BC would improve the prognosis for this large subset of patients. SPDEF was reported to be dysr...

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Detalles Bibliográficos
Autores principales: Li, Jingyuan, Wan, Xue, Xie, Dan, Yuan, Hui, Pei, Qin, Luo, Yanan, Chen, Yiyu, Xian, Jiawen, Ye, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460425/
https://www.ncbi.nlm.nih.gov/pubmed/37633945
http://dx.doi.org/10.1038/s41419-023-06098-z