The histone chaperone function of Daxx is dispensable for embryonic development

Daxx functions as a histone chaperone for the histone H3 variant, H3.3, and is essential for embryonic development. Daxx interacts with Atrx to form a protein complex that deposits H3.3 into heterochromatic regions of the genome, including centromeres, telomeres, and repeat loci. To advance our unde...

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Detalles Bibliográficos
Autores principales: Sun, Chang, Qi, Yuan, Fowlkes, Natalie, Lazic, Nina, Su, Xiaoping, Lozano, Guillermina, Wasylishen, Amanda R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460429/
https://www.ncbi.nlm.nih.gov/pubmed/37633949
http://dx.doi.org/10.1038/s41419-023-06089-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460429/
https://www.ncbi.nlm.nih.gov/pubmed/37633949
http://dx.doi.org/10.1038/s41419-023-06089-0

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