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The histone chaperone function of Daxx is dispensable for embryonic development
Daxx functions as a histone chaperone for the histone H3 variant, H3.3, and is essential for embryonic development. Daxx interacts with Atrx to form a protein complex that deposits H3.3 into heterochromatic regions of the genome, including centromeres, telomeres, and repeat loci. To advance our unde...
Autores principales: | Sun, Chang, Qi, Yuan, Fowlkes, Natalie, Lazic, Nina, Su, Xiaoping, Lozano, Guillermina, Wasylishen, Amanda R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460429/ https://www.ncbi.nlm.nih.gov/pubmed/37633949 http://dx.doi.org/10.1038/s41419-023-06089-0 |
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