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CRTAC1 enhances the chemosensitivity of non-small cell lung cancer to cisplatin by eliciting RyR-mediated calcium release and inhibiting Akt1 expression

Sensitivity to platinum-based combination chemotherapy is associated with a favorable prognosis in patients with non-small cell lung cancer (NSCLC). Here, our results obtained from analyses of the Gene Expression Omnibus database of NSCLC patients showed that cartilage acidic protein 1 (CRTAC1) play...

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Detalles Bibliográficos
Autores principales: Jin, Zihui, Zhao, Lingling, Chang, Yixin, Jin, Rongjia, Hu, Fangyu, Wu, Shuang, Xue, Zixuan, Ma, Yimeng, Chen, Chenglin, Zheng, Minghui, Chang, Yuanyuan, Jin, Honglei, Xie, Qipeng, Huang, Chuanshu, Huang, Haishan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460435/
https://www.ncbi.nlm.nih.gov/pubmed/37633993
http://dx.doi.org/10.1038/s41419-023-06088-1