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Co-amplification of CBX3 with EGFR or RAC1 in human cancers corroborated by a conserved genetic interaction among the genes

Chromobox Protein 3 (CBX3) overexpression is a common event occurring in cancer, promotes cancer cell proliferation and represents a poor prognosis marker in a plethora of human cancers. Here we describe that a wide spectrum of human cancers harbors a co-amplification of CBX3 gene with either EGFR o...

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Detalles Bibliográficos
Autores principales: Bosso, Giuseppe, Cipressa, Francesca, Tullo, Liliana, Cenci, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460438/
https://www.ncbi.nlm.nih.gov/pubmed/37633946
http://dx.doi.org/10.1038/s41420-023-01598-5