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Mutational landscape of intestinal crypt cells after long-term in vivo exposure to high fat diet

Obesity is a modifiable risk factor in cancer development, especially for gastrointestinal cancer. While the etiology of colorectal cancer is well characterized by the adenoma-carcinoma sequence, it remains unclear how obesity influences colorectal cancer development. Dietary components of a high fa...

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Detalles Bibliográficos
Autores principales: Meyenberg, Mathilde, Hakobyan, Anna, Papac-Milicevic, Nikolina, Göderle, Laura, Langner, Franziska L., Markovic, Mateo, Lee, Ji-Hyun, Koo, Bon-Kyoung, Busslinger, Georg A., da Silva, Israel Tojal, Binder, Christoph J., Menche, Jörg, Loizou, Joanna I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460443/
https://www.ncbi.nlm.nih.gov/pubmed/37633982
http://dx.doi.org/10.1038/s41598-023-41123-3