USP14 governs CYP2E1 to promote nonalcoholic fatty liver disease through deubiquitination and stabilization of HSP90AA1

Nonalcoholic fatty liver disease (NAFLD) begins with excessive triglyceride accumulation in the liver, and overly severe hepatic steatosis progresses to nonalcoholic steatohepatitis (NASH), which is characterized by lipid peroxidation, inflammation, and fibrosis. Ubiquitin-specific proteinase 14 (US...

Descripción completa

Detalles Bibliográficos
Autores principales: Wei, Dongqin, Tian, Xin, Zhu, Longbo, Wang, Han, Sun, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460448/
https://www.ncbi.nlm.nih.gov/pubmed/37633951
http://dx.doi.org/10.1038/s41419-023-06091-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460448/
https://www.ncbi.nlm.nih.gov/pubmed/37633951
http://dx.doi.org/10.1038/s41419-023-06091-6

Ejemplares similares