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Inhibition of CARM1 suppresses proliferation of multiple myeloma cells through activation of p53 signaling pathway

BACKGROUND: Multiple myeloma (MM) is a malignant proliferative disease of plasma cells, the incidence of which is increasing every year and remains incurable. The enzyme co-activator-associated arginine methyltransferase 1 (CARM1) is highly expressed in a variety of cancers, such as Hodgkin's l...

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Detalles Bibliográficos
Autores principales: Yang, Lan, Ma, Le, Gong, Qiang, Chen, JiePing, Huang, Qilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460731/
https://www.ncbi.nlm.nih.gov/pubmed/37477799
http://dx.doi.org/10.1007/s11033-023-08645-5