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A two-stages global sensitivity analysis by using the δ sensitivity index in presence of correlated inputs: application on a tumor growth inhibition model based on the dynamic energy budget theory
Global sensitivity analysis (GSA) evaluates the impact of variability and/or uncertainty of the model parameters on given model outputs. GSA is useful for assessing the quality of Pharmacometric model inference. Indeed, model parameters can be affected by high (estimation) uncertainty due to the spa...
Autores principales: | De Carlo, Alessandro, Tosca, Elena Maria, Melillo, Nicola, Magni, Paolo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460734/ https://www.ncbi.nlm.nih.gov/pubmed/37422844 http://dx.doi.org/10.1007/s10928-023-09872-w |
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