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Optimization of a Self-microemulsifying Drug Delivery System for Oral Administration of the Lipophilic Drug, Resveratrol: Enhanced Intestinal Permeability in Rat

PURPOSE: This study aimed to formulate Resveratrol, a practically water-insoluble antioxidant in a self-microemulsifying drug delivery system (SMEDDS) to improve the solubility, release rate, and intestinal permeability of the drug. METHODS: The suitable oil, surfactant, and co-surfactant were chose...

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Detalles Bibliográficos
Autores principales: Mirzaeei, Shahla, Tahmasebi, Negar, Islambulchilar, Ziba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460816/
https://www.ncbi.nlm.nih.gov/pubmed/37646050
http://dx.doi.org/10.34172/apb.2023.054