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Disruption of the Clock Component Bmal1 in Mice Promotes Cancer Metastasis through the PAI‐1‐TGF‐β‐myoCAF‐Dependent Mechanism

The circadian clock in animals and humans plays crucial roles in multiple physiological processes. Disruption of circadian homeostasis causes detrimental effects. Here, it is demonstrated that the disruption of the circadian rhythm by genetic deletion of mouse brain and muscle ARNT‐like 1 (Bmal1) ge...

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Detalles Bibliográficos
Autores principales: Wu, Jieyu, Jing, Xu, Du, Qiqiao, Sun, Xiaoting, Holgersson, Kristian, Gao, Juan, He, Xingkang, Hosaka, Kayoko, Zhao, Chen, Tao, Wei, FitzGerald, Garret A., Yang, Yunlong, Jensen, Lasse D., Cao, Yihai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460897/
https://www.ncbi.nlm.nih.gov/pubmed/37330661
http://dx.doi.org/10.1002/advs.202301505