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p62 and NBR1 functions are dispensable for aggrephagy in mouse ESCs and ESC-derived neurons

Accumulation of protein aggregates is a hallmark of various neurodegenerative diseases. Selective autophagy mediates the delivery of specific cytoplasmic cargo material into lysosomes for degradation. In aggrephagy, which is the selective autophagy of protein aggregates, the cargo receptors p62 and...

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Detalles Bibliográficos
Autores principales: Trapannone, Riccardo, Romanov, Julia, Martens, Sascha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460970/
https://www.ncbi.nlm.nih.gov/pubmed/37620146
http://dx.doi.org/10.26508/lsa.202301936