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p62 and NBR1 functions are dispensable for aggrephagy in mouse ESCs and ESC-derived neurons
Accumulation of protein aggregates is a hallmark of various neurodegenerative diseases. Selective autophagy mediates the delivery of specific cytoplasmic cargo material into lysosomes for degradation. In aggrephagy, which is the selective autophagy of protein aggregates, the cargo receptors p62 and...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10460970/ https://www.ncbi.nlm.nih.gov/pubmed/37620146 http://dx.doi.org/10.26508/lsa.202301936 |