TINF2 is a major susceptibility gene in Danish patients with multiple primary melanoma

TINF2 encodes the TINF2 protein, which is a subunit in the shelterin complex critical for telomere regulation. Three recent studies have associated six truncating germline variants in TINF2 that have previously been associated with a cancer predisposition syndrome (CPS) caused by elongation of the t...

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Detalles Bibliográficos
Autores principales: Jensen, Marlene Richter, Jelsig, Anne Marie, Gerdes, Anne-Marie, Hölmich, Lisbet Rosenkrantz, Kainu, Kati Hannele, Lorentzen, Henrik Frank, Hansen, Mary Højgaard, Bak, Mads, Johansson, Peter A., Hayward, Nicholas K., Van Overeem Hansen, Thomas, Wadt, Karin A.W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461021/
https://www.ncbi.nlm.nih.gov/pubmed/37646013
http://dx.doi.org/10.1016/j.xhgg.2023.100225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461021/
https://www.ncbi.nlm.nih.gov/pubmed/37646013
http://dx.doi.org/10.1016/j.xhgg.2023.100225

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