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Exacerbated lung inflammation following secondary RSV exposure is CD4+ T cell-dependent and is not mitigated in infant BALB/c mice born to PreF-vaccinated dams

Respiratory syncytial virus (RSV) is the leading cause of childhood hospitalizations due to bronchiolitis in children under 5 years of age. Moreover, severe RSV disease requiring hospitalization is associated with the subsequent development of wheezing and asthma. Due to the young age in which viral...

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Detalles Bibliográficos
Autores principales: Kosanovich, Jessica L., Eichinger, Katherine M., Lipp, Madeline A., Gidwani, Sonal V., Brahmbhatt, Devarshi, Yondola, Mark A., Perkins, Timothy N., Empey, Kerry M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461110/
https://www.ncbi.nlm.nih.gov/pubmed/37646035
http://dx.doi.org/10.3389/fimmu.2023.1206026