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Crisaborole Inhibits Itch and Pain by Preventing Neutrophil Infiltration in a Mouse Model of Atopic Dermatitis

Crisaborole, a phosphodiesterase 4 (PDE4) inhibitor, has been approved for the treatment of mild to moderate atopic dermatitis. Atopic dermatitis is often associated with increased pain. Using a mouse model, this study investigated whether crisaborole suppresses pain associated with atopic dermatiti...

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Detalles Bibliográficos
Autores principales: PAVLENKO, Darya, SEVEN, Zeynep Todurga, BYSTROM, Lauren, MARKAN, Anika, VERPILE, Rebecca, ISHIDA, Hirotake, AKIYAMA, Tasuku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medical Journals Sweden, on behalf of the Society for Publication of Acta Dermato-Venereologica 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461178/
https://www.ncbi.nlm.nih.gov/pubmed/37605895
http://dx.doi.org/10.2340/actadv.v103.13382