Re-Exploring the Anthracycline Chemical Space for Better Anti-Cancer Compounds

[Image: see text] The anthracycline anti-cancer drugs are intensely used in the clinic to treat a wide variety of cancers. They generate DNA double strand breaks, but recently the induction of chromatin damage was introduced as another major determinant of anti-cancer activity. The combination of th...

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Detalles Bibliográficos
Autores principales: van Gelder, Merle A., van der Zanden, Sabina Y., Vriends, Merijn B. L., Wagensveld, Roos A., van der Marel, Gijsbert A., Codée, Jeroen D. C., Overkleeft, Herman S., Wander, Dennis P. A., Neefjes, Jacques J. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461226/
https://www.ncbi.nlm.nih.gov/pubmed/37561481
http://dx.doi.org/10.1021/acs.jmedchem.3c00853

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461226/
https://www.ncbi.nlm.nih.gov/pubmed/37561481
http://dx.doi.org/10.1021/acs.jmedchem.3c00853

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