CD62L as target receptor for specific gene delivery into less differentiated human T lymphocytes

Chimeric antigen receptor (CAR)-expressing T cells are a complex and heterogeneous gene therapy product with variable phenotype compositions. A higher proportion of less differentiated CAR T cells is usually associated with improved antitumoral function and persistence. We describe in this study a n...

Descripción completa

Detalles Bibliográficos
Autores principales: Kapitza, Laura, Ho, Naphang, Kerzel, Thomas, Frank, Annika M., Thalheimer, Frederic B., Jamali, Arezoo, Schaser, Thomas, Buchholz, Christian J., Hartmann, Jessica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461316/
https://www.ncbi.nlm.nih.gov/pubmed/37646032
http://dx.doi.org/10.3389/fimmu.2023.1183698

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461316/
https://www.ncbi.nlm.nih.gov/pubmed/37646032
http://dx.doi.org/10.3389/fimmu.2023.1183698

Ejemplares similares