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NLRX1 can counteract innate immune response induced by an external stimulus favoring HBV infection by competitive inhibition of MAVS-RLRs signaling in HepG2-NTCP cells

INTRODUCTION: This study is aimed at the determination of the effect of the immune-regulatory factor NLRX1 on the antiviral activity of hepatocytes against an external stimuli favoring hepatitis B virus infection, and to explore its mechanism of action. METHODS: A HepG2-NTCP model was established us...

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Detalles Bibliográficos
Autores principales: Jiao, Qian, Xu, Wenxiong, Guo, Xiaoyan, Liu, Huiyuan, Liao, Baolin, Zhu, Xiang, Chen, Chuming, Yang, Fangji, Wu, Lina, Xie, Chan, Peng, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461377/
https://www.ncbi.nlm.nih.gov/pubmed/34825857
http://dx.doi.org/10.1177/00368504211058036