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NLRX1 can counteract innate immune response induced by an external stimulus favoring HBV infection by competitive inhibition of MAVS-RLRs signaling in HepG2-NTCP cells
INTRODUCTION: This study is aimed at the determination of the effect of the immune-regulatory factor NLRX1 on the antiviral activity of hepatocytes against an external stimuli favoring hepatitis B virus infection, and to explore its mechanism of action. METHODS: A HepG2-NTCP model was established us...
Autores principales: | Jiao, Qian, Xu, Wenxiong, Guo, Xiaoyan, Liu, Huiyuan, Liao, Baolin, Zhu, Xiang, Chen, Chuming, Yang, Fangji, Wu, Lina, Xie, Chan, Peng, Liang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461377/ https://www.ncbi.nlm.nih.gov/pubmed/34825857 http://dx.doi.org/10.1177/00368504211058036 |
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