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TFRC in cardiomyocytes promotes macrophage infiltration and activation during the process of heart failure through regulating Ccl2 expression mediated by hypoxia inducible factor‐1α

BACKGROUND: Cardiac hypertrophy is an initiating link to Heart failure (HF) which still seriously endangers human health. Transferrin receptor (TFRC), which promotes iron uptake through the transferrin cycle, is essential for cardiac function. However, whether TFRC is involved in the process of path...

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Detalles Bibliográficos
Autores principales: Pan, Yanyun, Yang, Jinxiu, Dai, Jin, Xu, Xiaoming, Zhou, Xinbin, Mao, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461419/
https://www.ncbi.nlm.nih.gov/pubmed/37647427
http://dx.doi.org/10.1002/iid3.835