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TFRC in cardiomyocytes promotes macrophage infiltration and activation during the process of heart failure through regulating Ccl2 expression mediated by hypoxia inducible factor‐1α
BACKGROUND: Cardiac hypertrophy is an initiating link to Heart failure (HF) which still seriously endangers human health. Transferrin receptor (TFRC), which promotes iron uptake through the transferrin cycle, is essential for cardiac function. However, whether TFRC is involved in the process of path...
Autores principales: | Pan, Yanyun, Yang, Jinxiu, Dai, Jin, Xu, Xiaoming, Zhou, Xinbin, Mao, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461419/ https://www.ncbi.nlm.nih.gov/pubmed/37647427 http://dx.doi.org/10.1002/iid3.835 |
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