Promoting the activity of a receptor tyrosine phosphatase with a novel pH‐responsive transmembrane agonist inhibits cancer‐associated phenotypes

Cell signaling by receptor protein tyrosine kinases (RTKs) is tightly controlled by the counterbalancing actions of receptor protein tyrosine phosphatases (RPTPs). Due to their role in attenuating the signal‐initiating potency of RTKs, RPTPs have long been viewed as therapeutic targets. However, the...

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Detalles Bibliográficos
Autores principales: Rizzo, Sophie, Sikorski, Eden, Park, Soohyung, Im, Wonpil, Vasquez‐Montes, Victor, Ladokhin, Alexey S., Thévenin, Damien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461461/
https://www.ncbi.nlm.nih.gov/pubmed/37515426
http://dx.doi.org/10.1002/pro.4742

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461461/
https://www.ncbi.nlm.nih.gov/pubmed/37515426
http://dx.doi.org/10.1002/pro.4742

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