TAF1B depletion leads to apoptotic cell death by inducing nucleolar stress and activating p53-miR-101 circuit in hepatocellular carcinoma

BACKGROUND: TAF1B (TATA Box Binding Protein (TBP)-Associated Factor) is an RNA polymerase regulating rDNA activity, stress response, and cell cycle. However, the function of TAF1B in the progression of hepatocellular carcinoma (HCC) is unknown. OBJECTIVE: In this study, we intended to characterize t...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Hang-fei, Gao, Dan-dan, Jiang, Xin-qing, Sheng, Hao, Wu, Qi, Zheng, Quan, Zhai, Qiao-cheng, Yuan, Lei, Liu, Ming, Xu, Li-feng, Qian, Mao-xiang, Xu, Heng, Fang, Jian, Zhang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461479/
https://www.ncbi.nlm.nih.gov/pubmed/37645431
http://dx.doi.org/10.3389/fonc.2023.1203775

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461479/
https://www.ncbi.nlm.nih.gov/pubmed/37645431
http://dx.doi.org/10.3389/fonc.2023.1203775

Ejemplares similares