Mathematical modeling clarifies the paracrine roles of insulin and glucagon on the glucose-stimulated hormonal secretion of pancreatic alpha- and beta-cells

INTRODUCTION: Blood sugar homeostasis relies largely on the action of pancreatic islet hormones, particularly insulin and glucagon. In a prototypical fashion, glucagon is released upon hypoglycemia to elevate glucose by acting on the liver while elevated glucose induces the secretion of insulin whic...

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Detalles Bibliográficos
Autores principales: Brown, Aedan, Tzanakakis, Emmanuel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461634/
https://www.ncbi.nlm.nih.gov/pubmed/37645413
http://dx.doi.org/10.3389/fendo.2023.1212749

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461634/
https://www.ncbi.nlm.nih.gov/pubmed/37645413
http://dx.doi.org/10.3389/fendo.2023.1212749

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