Novel anti-CD30/CD3 bispecific antibodies activate human T cells and mediate potent anti-tumor activity

CD30 is expressed on Hodgkin lymphomas (HL), many non-Hodgkin lymphomas (NHLs), and non-lymphoid malignancies in children and adults. Tumor expression, combined with restricted expression in healthy tissues, identifies CD30 as a promising immunotherapy target. An anti-CD30 antibody-drug conjugate (A...

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Detalles Bibliográficos
Autores principales: Faber, Mary L., Oldham, Robyn A. A., Thakur, Archana, Rademacher, Mary Jo, Kubicka, Ewa, Dlugi, Theresa A., Gifford, Steven A., McKillop, William M., Schloemer, Nathan J., Lum, Lawrence G., Medin, Jeffrey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461807/
https://www.ncbi.nlm.nih.gov/pubmed/37646042
http://dx.doi.org/10.3389/fimmu.2023.1225610

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461807/
https://www.ncbi.nlm.nih.gov/pubmed/37646042
http://dx.doi.org/10.3389/fimmu.2023.1225610

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