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Accurate detection of shared genetic architecture from GWAS summary statistics in the small-sample context
Assessment of the genetic similarity between two phenotypes can provide insight into a common genetic aetiology and inform the use of pleiotropy-informed, cross-phenotype analytical methods to identify novel genetic associations. The genetic correlation is a well-known means of quantifying and testi...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461826/ https://www.ncbi.nlm.nih.gov/pubmed/37585442 http://dx.doi.org/10.1371/journal.pgen.1010852 |