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Mechanism of substrate binding and transport in BASS transporters

The Bile Acid Sodium Symporter (BASS) family transports a wide array of molecules across membranes, including bile acids in humans, and small metabolites in plants. These transporters, many of which are sodium-coupled, have been shown to use an elevator mechanism of transport, but exactly how substr...

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Detalles Bibliográficos
Autores principales: Becker, Patrick, Naughton, Fiona B., Brotherton, Deborah H., Pacheco-Gomez, Raul, Beckstein, Oliver, Cameron, Alexander D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461908/
https://www.ncbi.nlm.nih.gov/pubmed/37645971
http://dx.doi.org/10.1101/2023.06.02.543391