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Isolation of the murine Glut1 deficient thalamocortical circuit: wavelet characterization and reverse glucose dependence of low and gamma frequency oscillations

Glucose represents the principal brain energy source. Thus, not unexpectedly, genetic glucose transporter 1 (Glut1) deficiency (G1D) manifests with encephalopathy. G1D seizures, which constitute a prominent disease manifestation, often prove refractory to medications but may respond to therapeutic d...

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Detalles Bibliográficos
Autores principales: Solis, Elysandra M., Good, Levi B., Granja Vázquez, Rafael, Patnaik, Sourav, Hernandez-Reynoso, Ana G., Ma, Qian, Angulo, Gustavo, Dobariya, Aksharkumar, Cogan, Stuart F., Pancrazio, Joseph J., Pascual, Juan M., Jakkamsetti, Vikram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461930/
https://www.ncbi.nlm.nih.gov/pubmed/37645928
http://dx.doi.org/10.1101/2023.06.05.543611