IL-6–Dependent STAT3 Activation and Induction of Proinflammatory Cytokines in Primary Sclerosing Cholangitis

INTRODUCTION: Primary sclerosing cholangitis (PSC) is a rare cholestatic liver disease with periductal inflammation and fibrosis. Genetic studies suggest inflammatory cytokines and IL-6–dependent activation of transcription factor STAT3 as pivotal steps in PSC pathogenesis. However, details of infla...

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Detalles Bibliográficos
Autores principales: Dold, Leona, Frank, Leonie, Lutz, Philipp, Kaczmarek, Dominik J., Krämer, Benjamin, Nattermann, Jacob, Weismüller, Tobias J., Branchi, Vittorio, Toma, Marieta, Gonzalez-Carmona, Maria, Strassburg, Christian P., Spengler, Ulrich, Langhans, Bettina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461951/
https://www.ncbi.nlm.nih.gov/pubmed/37256725
http://dx.doi.org/10.14309/ctg.0000000000000603

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461951/
https://www.ncbi.nlm.nih.gov/pubmed/37256725
http://dx.doi.org/10.14309/ctg.0000000000000603

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