Two-way feedback between chromatin compaction and histone modification state explains S. cerevisiae heterochromatin bistability

Compact chromatin is closely linked with gene silencing in part by sterically masking access to promoters, inhibiting transcription factor binding and preventing polymerase from efficiently transcribing a gene. Here, we propose a broader view: chromatin compaction can be both a cause and a consequen...

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Detalles Bibliográficos
Autores principales: Miangolarra, Ander Movilla, Saxton, Daniel S, Yan, Zhi, Rine, Jasper, Howard, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461966/
https://www.ncbi.nlm.nih.gov/pubmed/37645983
http://dx.doi.org/10.1101/2023.08.12.552948

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461966/
https://www.ncbi.nlm.nih.gov/pubmed/37645983
http://dx.doi.org/10.1101/2023.08.12.552948

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