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Two-way feedback between chromatin compaction and histone modification state explains S. cerevisiae heterochromatin bistability
Compact chromatin is closely linked with gene silencing in part by sterically masking access to promoters, inhibiting transcription factor binding and preventing polymerase from efficiently transcribing a gene. Here, we propose a broader view: chromatin compaction can be both a cause and a consequen...
Autores principales: | Miangolarra, Ander Movilla, Saxton, Daniel S, Yan, Zhi, Rine, Jasper, Howard, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461966/ https://www.ncbi.nlm.nih.gov/pubmed/37645983 http://dx.doi.org/10.1101/2023.08.12.552948 |
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