Rapid ionic current phenotyping (RICP) identifies mechanistic underpinnings of iPSC-CM AP heterogeneity

As a renewable, easily accessible, human-derived in vitro model, human induced pluripotent stem cell derived cardiomyocytes (iPSC-CMs) are a promising tool for studying arrhythmia-related factors, including cardiotoxicity and congenital proarrhythmia risks. An oft-mentioned limitation of iPSC-CMs is...

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Detalles Bibliográficos
Autores principales: Clark, Alexander P., Wei, Siyu, Fullerton, Kristin, Krogh-Madsen, Trine, Christini, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461967/
https://www.ncbi.nlm.nih.gov/pubmed/37645815
http://dx.doi.org/10.1101/2023.08.16.553521

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461967/
https://www.ncbi.nlm.nih.gov/pubmed/37645815
http://dx.doi.org/10.1101/2023.08.16.553521

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