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Bioluminescence Assay of Lysine Deacylase Sirtuin Activity

Lysine acylation can direct protein function, localization, and interactions. Sirtuins deacylate lysine towards maintaining cellular homeostasis, and their aberrant expression contributes to the pathogenesis of multiple pathological conditions, including cancer. Measuring sirtuins’ activity is essen...

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Detalles Bibliográficos
Autores principales: Van Scoyk, Alexandria N., Antelope, Orlando, Franzini, Anca, Ayer, Donald E., Peterson, Randall T., Pomicter, Anthony D., Owen, Shawn C., Deininger, Michael W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461969/
https://www.ncbi.nlm.nih.gov/pubmed/37645727
http://dx.doi.org/10.1101/2023.08.10.552871