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Highly multiplexed mRNA quantitation with CRISPR-Cas13

RNA quantitation tools are often either high-throughput or cost-effective, but rarely are they both. Existing methods can profile the transcriptome at great expense or are limited to quantifying a handful of genes by labor constraints. A technique that permits more throughput at a reduced cost could...

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Detalles Bibliográficos
Autores principales: Kang, Brian, Zhang, Jiayu, Schwoerer, Michael P., Nelson, Amy N., Schoeman, Emily, Guo, Andrew, Ploss, Alexander, Myhrvold, Cameron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461975/
https://www.ncbi.nlm.nih.gov/pubmed/37645785
http://dx.doi.org/10.1101/2023.08.16.553527