Characterization of enhancer activity in early human neurodevelopment using Massively parallel reporter assay (MPRA) and forebrain organoids

Regulation of gene expression through enhancers is one of the major processes shaping the structure and function of the human brain during development. High-throughput assays have predicted thousands of enhancers involved in neurodevelopment, and confirming their activity through orthogonal function...

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Detalles Bibliográficos
Autores principales: Capauto, Davide, Wang, Yifan, Wu, Feinan, Norton, Scott, Mariani, Jessica, Inoue, Fumitaka, Crawford, Gregory E., Ahituv, Nadav, Abyzov, Alexej, Vaccarino, Flora M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461976/
https://www.ncbi.nlm.nih.gov/pubmed/37645832
http://dx.doi.org/10.1101/2023.08.14.553170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461976/
https://www.ncbi.nlm.nih.gov/pubmed/37645832
http://dx.doi.org/10.1101/2023.08.14.553170

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