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Deconstructing Intratumoral Heterogeneity through Multiomic and Multiscale Analysis of Serial Sections
Cancerous tumors may contain billions of cells including distinct malignant clones and nonmalignant cell types. Clarifying the evolutionary histories, prevalence, and defining molecular features of these cells is essential for improving clinical outcomes, since intratumoral heterogeneity provides fu...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461981/ https://www.ncbi.nlm.nih.gov/pubmed/37645893 http://dx.doi.org/10.1101/2023.06.21.545365 |