Deconstructing Intratumoral Heterogeneity through Multiomic and Multiscale Analysis of Serial Sections

Cancerous tumors may contain billions of cells including distinct malignant clones and nonmalignant cell types. Clarifying the evolutionary histories, prevalence, and defining molecular features of these cells is essential for improving clinical outcomes, since intratumoral heterogeneity provides fu...

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Detalles Bibliográficos
Autores principales: Schupp, Patrick G., Shelton, Samuel J., Brody, Daniel J., Eliscu, Rebecca, Johnson, Brett E., Mazor, Tali, Kelley, Kevin W., Potts, Matthew B., McDermott, Michael W., Huang, Eric J., Lim, Daniel A., Pieper, Russell O., Berger, Mitchel S., Costello, Joseph F., Phillips, Joanna J., Oldham, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461981/
https://www.ncbi.nlm.nih.gov/pubmed/37645893
http://dx.doi.org/10.1101/2023.06.21.545365

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