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Exploring Temporal and Sex-Linked Dysregulation in Alzheimer’s Disease Phospho-Proteome

This study aims to characterize dysregulation of phosphorylation for the 5XFAD mouse model of Alzheimer’s disease (AD). Employing global phosphoproteome measurements, we analyze temporal (3, 6, 9 months) and sex-dependent effects on mouse hippocampus tissue to unveil molecular signatures associated...

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Detalles Bibliográficos
Autores principales: Yılmaz, Serhan, Pereira Lopes, Filipa Blasco Tavares, Schlatzer, Daniela, Wang, Rihua, Qi, Xin, Koyutürk, Mehmet, Chance, Mark R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461982/
https://www.ncbi.nlm.nih.gov/pubmed/37645993
http://dx.doi.org/10.1101/2023.08.15.553056