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Hedgehog signaling is required for the maintenance of mesenchymal nephron progenitors
BACKGROUND: Mesenchymal nephron progenitors (mNPs) give rise to all nephron tubules in the mammalian kidney. Since premature depletion of these cells leads to low nephron numbers, high blood pressure, and various renal diseases, it is critical to understand how mNPs are maintained. While Fgf, Bmp, a...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461989/ https://www.ncbi.nlm.nih.gov/pubmed/37645929 http://dx.doi.org/10.1101/2023.08.12.553098 |