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Hedgehog signaling is required for the maintenance of mesenchymal nephron progenitors

BACKGROUND: Mesenchymal nephron progenitors (mNPs) give rise to all nephron tubules in the mammalian kidney. Since premature depletion of these cells leads to low nephron numbers, high blood pressure, and various renal diseases, it is critical to understand how mNPs are maintained. While Fgf, Bmp, a...

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Detalles Bibliográficos
Autores principales:	Chung, Eunah, Deacon, Patrick, Hu, Yueh-Chiang, Lim, Hee-Woong, Park, Joo-Seop
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461989/ https://www.ncbi.nlm.nih.gov/pubmed/37645929 http://dx.doi.org/10.1101/2023.08.12.553098

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