Molecular dynamics analyses of CLDN15 pore size and charge selectivity

The Claudin-15 (CLDN15) channel is important for nutrient, electrolyte, and water transport in the gastrointestinal tract. We used cell culture studies and molecular dynamics simulations to elucidate its structure and permeability mechanisms. We provide a model that underscores the crucial role of t...

Descripción completa

Detalles Bibliográficos
Autores principales: McGuinness, Sarah, Li, Pan, Li, Ye, Fuladi, Shadi, Konar, Sukanya, Sajjadi, Samaneh, Sidahmed, Mohammed, Li, Yueying, Shen, Le, Araghi, Fatemeh Khalili, Weber, Christopher R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461993/
https://www.ncbi.nlm.nih.gov/pubmed/37645840
http://dx.doi.org/10.1101/2023.08.16.553400

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461993/
https://www.ncbi.nlm.nih.gov/pubmed/37645840
http://dx.doi.org/10.1101/2023.08.16.553400

Ejemplares similares