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Structure of C. elegans TMC-2 complex suggests roles of lipid-mediated subunit contacts in mechanosensory transduction

Mechanotransduction is the process by which a mechanical force, such as touch, is converted into an electrical signal. Transmembrane channel-like (TMC) proteins are an evolutionarily-conserved family of ion channels whose function has been linked to a variety of mechanosensory processes, including h...

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Detalles Bibliográficos
Autores principales: Clark, Sarah, Jeong, Hanbin, Posert, Rich, Goehring, April, Gouaux, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462014/
https://www.ncbi.nlm.nih.gov/pubmed/37645790
http://dx.doi.org/10.1101/2023.08.16.553618