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Identification of HPV oncogene and host cell differentiation associated cellular heterogeneity in cervical cancer via single-cell transcriptomic analysis

Human Papillomaviruses (HPVs) are associated with around 5–10% of human cancer, notably nearly 99% of cervical cancer. The mechanisms HPV interacts with stratified epithelium (differentiated layers) during the viral life cycle, and oncogenesis remain unclear. In this study, we used single-cell trans...

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Detalles Bibliográficos
Autores principales: Li, Yingjie, Wang, Cankun, Ma, Anjun, Rani, Abdul Qawee, Luo, Mingjue, Li, Jenny, Liu, Xuefeng, Ma, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462038/
https://www.ncbi.nlm.nih.gov/pubmed/37645794
http://dx.doi.org/10.1101/2023.08.10.552878