The 3’ exonuclease TOE1 selectively processes snRNAs through recognition of Sm complex assembly and 5’ cap trimethylation

Competing exonucleases that promote 3’ end maturation or degradation direct quality control of small non-coding RNAs, but how these enzymes distinguish normal from aberrant RNAs is poorly understood. The Pontocerebellar Hypoplasia 7 (PCH7)-associated 3’ exonuclease TOE1 promotes maturation of canoni...

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Detalles Bibliográficos
Autores principales: Ma, Tiantai, Xiong, Erica S, Lardelli, Rea M, Lykke-Andersen, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462049/
https://www.ncbi.nlm.nih.gov/pubmed/37645788
http://dx.doi.org/10.1101/2023.08.15.553431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462049/
https://www.ncbi.nlm.nih.gov/pubmed/37645788
http://dx.doi.org/10.1101/2023.08.15.553431

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