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Control of G protein-coupled receptor function via membrane-interacting intrinsically disordered C-terminal domains
G protein-coupled receptors (GPCRs) control intracellular signaling cascades via agonist-dependent coupling to intracellular transducers including heterotrimeric G proteins, GPCR kinases (GRKs), and arrestins. In addition to their critical interactions with the transmembrane core of active GPCRs, al...
Autores principales: | Mancinelli, Chiara, Marx, Dagan C., Gonzalez-Hernandez, Alberto J., Mancinelli, Lucia, Khelashvilli, George, Levitz, Joshua, Eliezer, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462050/ https://www.ncbi.nlm.nih.gov/pubmed/37645938 http://dx.doi.org/10.1101/2023.08.16.553551 |
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