Mucus physically restricts influenza A viral particle access to the epithelium

Prior work suggests influenza A virus (IAV) crosses the airway mucus barrier in a sialic acid-dependent manner through the actions of the viral envelope proteins, hemagglutinin and neuraminidase. However, host and viral factors that influence how efficiently mucus traps IAV remain poorly defined. In...

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Detalles Bibliográficos
Autores principales: Kaler, Logan, Engle, Elizabeth M., Iverson, Ethan, Boboltz, Allison, Ignacio, Maxinne A., Rife, Maria, Scull, Margaret A., Duncan, Gregg A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462089/
https://www.ncbi.nlm.nih.gov/pubmed/37645821
http://dx.doi.org/10.1101/2023.08.14.553271

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462089/
https://www.ncbi.nlm.nih.gov/pubmed/37645821
http://dx.doi.org/10.1101/2023.08.14.553271

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