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Predicting host-based, synthetic lethal antiviral targets from omics data

Traditional antiviral therapies often have limited effectiveness due to toxicity and development of drug resistance. Host-based antivirals, while an alternative, may lead to non-specific effects. Recent evidence shows that virus-infected cells can be selectively eliminated by targeting synthetic let...

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Detalles Bibliográficos
Autores principales: Staheli, Jeannette P., Neal, Maxwell L., Navare, Arti, Mast, Fred D., Aitchison, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462099/
https://www.ncbi.nlm.nih.gov/pubmed/37645861
http://dx.doi.org/10.1101/2023.08.15.553430